Anti-Human RAB27B Polyclonal Antibody (HT029014)

Name: Anti-Human RAB27B Polyclonal Antibody
Brand: abinScience
SKU: HT029014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HT029014

Описание

Anti-Human RAB27B Polyclonal Antibody (HT029014) is a rabbit polyclonal antibody detecting RAB27B in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human RAB27B (Met1-Asp196).

Цель

RAB27B, Ras-related protein Rab-27B, C25KG

Очистка

Purified by antigen affinity column.

Номер доступа

O00194

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Ras-related protein Rab-27B (RAB27B) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB27B regulates homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1. May be involved in targeting uroplakins to urothelial apical membranes.

1. Huang, SH. et al. (2011) The Journal of neuroscience : the official journal of the Society for Neuroscience 31, 10602-14. PMID: 21775604

2. Zhang, J. et al. (2019) Biochimica et biophysica acta. Molecular cell research 1866, 916-929. PMID: 30771381

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human RAB27B Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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