

| Каталожный номер | HC569014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human RAB31 Polyclonal Antibody (HC569014) is a rabbit polyclonal antibody detecting RAB31 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RAB31 (Met1-Gln165). | ||||||||
| Цель | Ras-related protein Rab-22B, Ras-related protein Rab-31, RAB22B, RAB31 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q13636 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ras-related protein Rab-31 (RAB31) is a ~21 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. 1. Bao, X. et al. (2002) European journal of biochemistry 269, 259-71. PMID: 11784320 | ||||||||
| Примечание | For research use only. |
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