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Anti-Human RAB39B Monoclonal Antibody (1A444) (HP954025)

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Anti-Human RAB39B Monoclonal Antibody (1A444)
Anti-Human RAB39B Monoclonal Antibody (1A444)
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Vista general
Número de catálogoHP954025
Descripción
Anti-Human RAB39B Monoclonal Antibody (1A444) [1A444] (HP954025) is a mouse monoclonal antibody detecting RAB39B in ELISA, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
Reactividad de especiesHuman
AplicacionesELISA, WB
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1
ID de clon1A444
Inmunógeno Recombinant Human RAB39B protein.
Objetivo Ras-related protein Rab-39B, RAB39B
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q96DA2
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Ras-related protein Rab-39B (RAB39B) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB39B is involved in autophagy and may function in autophagosome formation. Binds downstream effector PICK1 to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR composition at the post-synapses and thus synaptic transmission. May regulate the homeostasis of SNCA/alpha-synuclein.

1. Sellier, C. et al. (2016) The EMBO journal 35, 1276-97. PMID: 27103069
2. Zhang, S. et al. (2023) Nature communications 14, 6360. PMID: 37821429
Nota For research use only.
Imágenes
  • Anti-Human RAB39B Monoclonal Antibody (1A444)

    SDS-PAGE

    SDS-PAGE for Anti-Human RAB39B Monoclonal Antibody (1A444)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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