Anti-Human RAB39B Monoclonal Antibody (1A444) (HP954025)

Name: Anti-Human RAB39B Monoclonal Antibody (1A444)
Brand: abinScience
SKU: HP954025
Price: 106 USD
Availability: InStock

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Каталожный номер	HP954025
Описание	Anti-Human RAB39B Monoclonal Antibody (1A444) [1A444] (HP954025) is a mouse monoclonal antibody detecting RAB39B in ELISA, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
Реактивность видов	Human
Применения	ELISA, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1
ID клона	1A444
Иммуноген	Recombinant Human RAB39B protein.
Цель	Ras-related protein Rab-39B, RAB39B
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	Q96DA2
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Ras-related protein Rab-39B (RAB39B) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB39B is involved in autophagy and may function in autophagosome formation. Binds downstream effector PICK1 to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR composition at the post-synapses and thus synaptic transmission. May regulate the homeostasis of SNCA/alpha-synuclein. 1. Sellier, C. et al. (2016) The EMBO journal 35, 1276-97. PMID: 27103069 2. Zhang, S. et al. (2023) Nature communications 14, 6360. PMID: 37821429
Примечание	For research use only.

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Anti-Human RAB39B Monoclonal Antibody (1A444).pdf

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Anti-Human RAB39B Monoclonal Antibody (1A444) (HP954025)

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