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| カタログ番号 | HB122014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RAC2 Polyclonal Antibody (HB122014) is a rabbit polyclonal antibody detecting RAC2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RAC2 (Met1-Leu192). | ||||||||
| ターゲット | Small G protein, GX, p21-Rac2, Ras-related C3 botulinum toxin substrate 2, RAC2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P15153 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ras-related C3 botulinum toxin substrate 2 (RAC2) is a ~21 kDa protein. Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In its active state, binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Regulatory subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). 1. Hsu, AP. et al. (2019) Blood 133, 1977-1988. PMID: 30723080 2. Knaus, UG. et al. (1991) Science (New York, N.Y.) 254, 1512-5. PMID: 1660188 | ||||||||
| 注意事項 | For research use only. |
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