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| カタログ番号 | HY382014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RALB Polyclonal Antibody (HY382014) is a rabbit polyclonal antibody detecting RALB in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RALB (Ser11-Leu206). | ||||||||
| ターゲット | Ras-related protein Ral-B, RALB | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11234 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ras-related protein Ral-B (RALB) is a ~23 kDa protein. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Required for suppression of apoptosis. 1. Nakashima, S. et al. (1999) The EMBO journal 18, 3629-42. PMID: 10393179 2. Falsetti, SC. et al. (2007) Molecular and cellular biology 27, 8003-14. PMID: 17875936 3. Cascone, I. et al. (2008) The EMBO journal 27, 2375-87. PMID: 18756269 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-RALB polyclonal antibody at 1ug/mL on various samples.
Lane 1: MCF-7 cell lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse lung lysate
Lane 4: Rat brain lysate
Lane 5: Rat lung lysate
Lane 6: Rat kidney lysate
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