

| Numéro de catalogue | HF873014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RAMP1 Polyclonal Antibody (HF873014) is a rabbit polyclonal antibody detecting RAMP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human RAMP1 (Cys27-Leu119). | ||||||||
| Cible | Receptor activity-modifying protein 1, Calcitonin-receptor-like receptor activity-modifying protein 1, CRLR activity-modifying protein 1, RAMP1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O60894 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Receptor activity-modifying protein 1 (RAMP1) is a ~16 kDa protein. Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA. 1. Josephs, TM. et al. (2021) Science (New York, N.Y.) 372. PMID: 33602864 2. McLatchie, LM. et al. (1998) Nature 393, 333-9. PMID: 9620797 3. Cao, J. et al. (2022) Science (New York, N.Y.) 375, eabm9609. PMID: 35324283 4. Cao, J. et al. (2024) Biochemistry 63, 1089-1096. PMID: 38603770 | ||||||||
| Note | For research use only. |
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