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Anti-Human RANBP9 Polyclonal Antibody (HP154014)

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Número de catálogoHP154014
Descripción
Anti-Human RANBP9 Polyclonal Antibody (HP154014) is a rabbit polyclonal antibody detecting RANBP9 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RANBP9 (Ser176-Gly330).
Objetivo RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM
Purificación Purified by antigen affinity column.
Número de acceso Q96S59
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Ran-binding protein 9 (RANBP9) is a ~77 kDa protein. May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.

1. Valiyaveettil, M. et al. (2008) The Journal of cell biology 182, 727-39. PMID: 18710924
2. Lampert, F. et al. (2018) eLife 7. PMID: 29911972
3. Denti, S. et al. (2004) The Journal of biological chemistry 279, 13027-34. PMID: 14722085
4. Wang, D. et al. (2002) The Journal of biological chemistry 277, 36216-22. PMID: 12147692
5. Rao, MA. et al. (2002) The Journal of biological chemistry 277, 48020-7. PMID: 12361945
6. Harada, N. et al. (2008) Biochemical and biophysical research communications 368, 121-5. PMID: 18222118
7. Kramer, S. et al. (2005) Oncogene 24, 938-44. PMID: 15558019
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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