Anti-Human RANBP9 Polyclonal Antibody (HP154014)

Name: Anti-Human RANBP9 Polyclonal Antibody
Brand: abinScience
SKU: HP154014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HP154014

説明

Anti-Human RANBP9 Polyclonal Antibody (HP154014) is a rabbit polyclonal antibody detecting RANBP9 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human RANBP9 (Ser176-Gly330).

ターゲット

RanBP7, RanBPM, RanBP9, Ran-binding protein 9, Ran-binding protein M, BPM90, RANBP9, BPM-L, RANBPM

精製

Purified by antigen affinity column.

アクセッション番号

Q96S59

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Ran-binding protein 9 (RANBP9) is a ~77 kDa protein. May act as scaffolding protein, and as adapter protein to couple membrane receptors to intracellular signaling pathways (Probable). Acts as a mediator of cell spreading and actin cytoskeleton rearrangement. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway.

1. Valiyaveettil, M. et al. (2008) The Journal of cell biology 182, 727-39. PMID: 18710924

2. Lampert, F. et al. (2018) eLife 7. PMID: 29911972

3. Denti, S. et al. (2004) The Journal of biological chemistry 279, 13027-34. PMID: 14722085

4. Wang, D. et al. (2002) The Journal of biological chemistry 277, 36216-22. PMID: 12147692

5. Rao, MA. et al. (2002) The Journal of biological chemistry 277, 48020-7. PMID: 12361945

6. Harada, N. et al. (2008) Biochemical and biophysical research communications 368, 121-5. PMID: 18222118

7. Kramer, S. et al. (2005) Oncogene 24, 938-44. PMID: 15558019

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human RANBP9 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human RANBP9 Polyclonal Antibody (HP154014)

概要

イメージ

参考文献

データシート

SDS