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| カタログ番号 | HY078014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RAP2A Polyclonal Antibody (HY078014) is a rabbit polyclonal antibody detecting RAP2A in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RAP2A (Met1-Gln183). | ||||||||
| ターゲット | Ras-related protein Rap-2a, 3.6.5.2, RbBP-30, RAP2A | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P10114 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ras-related protein Rap-2a (RAP2A) is a ~20 kDa protein. Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and regulates cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. 1. Machida, N. et al. (2004) The Journal of biological chemistry 279, 15711-4. PMID: 14966141 2. Taira, K. et al. (2004) The Journal of biological chemistry 279, 49488-96. PMID: 15342639 3. Mittal, V. et al. (2006) The Biochemical journal 394, 309-15. PMID: 16246175 4. Greco, F. et al. (2006) Biochimica et biophysica acta 1763, 330-5. PMID: 16540189 5. Nonaka, H. et al. (2008) Biochemical and biophysical research communications 377, 573-578. PMID: 18930710 6. Kawabe, H. et al. (2010) Neuron 65, 358-72. PMID: 20159449 7. Duncan, ED. et al. (2022) The Journal of cell biology 221. PMID: 35293963 | ||||||||
| 注意事項 | For research use only. |
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