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Anti-Human RARB Polyclonal Antibody (HY385014)

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Anti-Human RARB Polyclonal Antibody
Anti-Human RARB Polyclonal Antibody
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Vista general
Número de catálogoHY385014
Descripción
Anti-Human RARB Polyclonal Antibody (HY385014) is a rabbit polyclonal antibody detecting RARB in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RARB (Leu205-Ser451).
Objetivo Retinoic acid receptor beta, Nuclear receptor subfamily 1 group B member 2, RARB, HBV-activated protein, RAR-beta, RAR-epsilon, NR1B2, HAP
Purificación Purified by antigen affinity column.
Número de acceso P10826
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Retinoic acid receptor beta (RARB) is a ~50 kDa protein. Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element.

1. Hauksdottir, H. et al. (2003) Molecular endocrinology (Baltimore, Md.) 17, 373-85. PMID: 12554770
2. Chandra, V. et al. (2017) Nature communications 8, 868. PMID: 29021580
Nota For research use only.
Imágenes
  • Anti-Human RARB Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-RARB polyclonal antibody at 1ug/mL on various samples.
    Lane 1: HUVEC cell lysate
    Lane 2: A431 cell lysate
    Lane 3: A549 cell lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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