

| Каталожный номер | HS761013 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Human | ||||
| Применения | ELISA, IF, IP | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | IgG2a | ||||
| ID клона | SAA0256 | ||||
| Цель | Retinoblastoma-binding protein 5, Retinoblastoma-binding protein RBQ-3, RBQ3, RBBP-5, RBBP5 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q15291 | ||||
| RRID | Anti-Human RBBP5 IP Antibody (SAA0256) (abinScience Cat# HS761013, RRID:AB_3729790) |
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| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Фон | Retinoblastoma-binding protein 5 (RBBP5) is a ~59 kDa protein. In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. 1. Garapaty, S. et al. (2009) The Journal of biological chemistry 284, 7542-52. PMID: 19131338 2. Patel, A. et al. (2009) The Journal of biological chemistry 284, 24242-56. PMID: 19556245 3. Avdic, V. et al. (2011) Structure (London, England : 1993) 19, 101-8. PMID: 21220120 4. Zhang, P. et al. (2012) Nucleic acids research 40, 4237-46. PMID: 22266653 | ||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human RBBP5 IP Antibody (SAA0256)
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