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| カタログ番号 | HF627014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RBBP9 Polyclonal Antibody (HF627014) is a rabbit polyclonal antibody detecting RBBP9 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RBBP9 (Met1-Ala186). | ||||||||
| ターゲット | BOG, RBBP9, B5T-overexpressed gene protein, RBBP10, Serine hydrolase RBBP9, RBBP-9, Retinoblastoma-binding protein 9, Protein BOG, Retinoblastoma-binding protein 10, RBBP-10 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O75884 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Serine hydrolase RBBP9 is a ~21 kDa protein. Serine hydrolase (Probable). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. 1. Shenoy, VM. et al. (2020) Molecular pharmaceutics 17, 1706-1714. PMID: 32196348 2. Shields, DJ. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 2189-94. PMID: 20080647 3. Woitach, JT. et al. (1998) Nature genetics 19, 371-4. PMID: 9697699 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-MMAB polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: HepG2 cell lysate
Lane 3: A549 cell lysate
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