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Anti-Human RBM39 Polyclonal Antibody (HC636014)

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Vista general
Número de catálogoHC636014
Descripción
Anti-Human RBM39 Polyclonal Antibody (HC636014) is a rabbit polyclonal antibody detecting RBM39 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RBM39 (Thr146-Val326).
Objetivo CAPER alpha, RNA-binding protein 39, RNA-binding region-containing protein 2, CAPERalpha, HCC1, RNPC2, RBM39, RNA-binding motif protein 39, Hepatocellular carcinoma protein 1, Splicing factor HCC1
Purificación Purified by antigen affinity column.
Número de acceso Q14498
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

RNA-binding protein 39 (RBM39) is a ~59 kDa protein. RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity.

1. Dowhan, DH. et al. (2005) Molecular cell 17, 429-39. PMID: 15694343
2. Loerch, S. et al. (2014) The Journal of biological chemistry 289, 17325-37. PMID: 24795046
3. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793
4. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394
5. Tari, M. et al. (2019) EMBO reports 20, e47604. PMID: 31271494
Nota For research use only.
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Referencias
Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human RBM39 Polyclonal Antibody

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