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Anti-Human RBM39 Polyclonal Antibody (HC636014)

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Aperçu
Numéro de catalogueHC636014
Description
Anti-Human RBM39 Polyclonal Antibody (HC636014) is a rabbit polyclonal antibody detecting RBM39 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human RBM39 (Thr146-Val326).
Cible CAPER alpha, RNA-binding protein 39, RNA-binding region-containing protein 2, CAPERalpha, HCC1, RNPC2, RBM39, RNA-binding motif protein 39, Hepatocellular carcinoma protein 1, Splicing factor HCC1
Purification Purified by antigen affinity column.
Numéro d'accès Q14498
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

RNA-binding protein 39 (RBM39) is a ~59 kDa protein. RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity.

1. Dowhan, DH. et al. (2005) Molecular cell 17, 429-39. PMID: 15694343
2. Loerch, S. et al. (2014) The Journal of biological chemistry 289, 17325-37. PMID: 24795046
3. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793
4. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394
5. Tari, M. et al. (2019) EMBO reports 20, e47604. PMID: 31271494
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Volume
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g/mol
Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human RBM39 Polyclonal Antibody

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