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| カタログ番号 | HC636014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RBM39 Polyclonal Antibody (HC636014) is a rabbit polyclonal antibody detecting RBM39 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RBM39 (Thr146-Val326). | ||||||||
| ターゲット | CAPER alpha, RNA-binding protein 39, RNA-binding region-containing protein 2, CAPERalpha, HCC1, RNPC2, RBM39, RNA-binding motif protein 39, Hepatocellular carcinoma protein 1, Splicing factor HCC1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q14498 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | RNA-binding protein 39 (RBM39) is a ~59 kDa protein. RNA-binding protein that acts as a pre-mRNA splicing factor. Acts by promoting exon inclusion via regulation of exon cassette splicing. Also acts as a transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1, independently of the pre-mRNA splicing factor activity. 1. Dowhan, DH. et al. (2005) Molecular cell 17, 429-39. PMID: 15694343 2. Loerch, S. et al. (2014) The Journal of biological chemistry 289, 17325-37. PMID: 24795046 3. Han, T. et al. (2017) Science (New York, N.Y.) 356. PMID: 28302793 4. Uehara, T. et al. (2017) Nature chemical biology 13, 675-680. PMID: 28437394 5. Tari, M. et al. (2019) EMBO reports 20, e47604. PMID: 31271494 | ||||||||
| 注意事項 | For research use only. |
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