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Anti-Human RBX1 Polyclonal Antibody (HX852014)

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Aperçu
Numéro de catalogueHX852014
Description
Anti-Human RBX1 Polyclonal Antibody (HX852014) is a rabbit polyclonal antibody detecting RBX1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human RBX1 (Ala2-Arg46).
Cible RING finger protein 75, RNF75, E3 ubiquitin-protein transferase RBX1, N-terminally processed, RBX1, E3 ubiquitin-protein ligase RBX1, Rbx1, ROC1, E3 ubiquitin-protein transferase RBX1, Protein ZYP, RING-box protein 1, Regulator of cullins 1
Purification Purified by antigen affinity column.
Numéro d'accès P62877
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

E3 ubiquitin-protein ligase RBX1 is a ~12 kDa protein. E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex mediates ubiquitination of Pol II subunit POLR2A at 'Lys-1268', a critical TC-NER checkpoint. Core component of the Cul7-RING(FBXW8) ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

1. Ohta, T. et al. (1999) Molecular cell 3, 535-41. PMID: 10230407
2. Kamura, T. et al. (1999) Genes & development 13, 2928-33. PMID: 10579999
3. Zheng, N. et al. (2002) Nature 416, 703-9. PMID: 11961546
4. Zhang, DD. et al. (2005) The Journal of biological chemistry 280, 30091-9. PMID: 15983046
5. Wang, H. et al. (2006) Molecular cell 22, 383-94. PMID: 16678110
6. Cen, B. et al. (2009) The Journal of biological chemistry 284, 5265-76. PMID: 19112177
7. Isobe, T. et al. (2009) The Journal of biological chemistry 284, 27766-27779. PMID: 19679664
8. Duda, DM. et al. (2012) Molecular cell 47, 371-82. PMID: 22748924
9. Beck, J. et al. (2013) Nature cell biology 15, 430-9. PMID: 23455478
10. Scott, DC. et al. (2016) Cell 166, 1198-1214.e24. PMID: 27565346
Note For research use only.
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Formula
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Anti-Human RBX1 Polyclonal Antibody

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