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Anti-Human RCC2 Polyclonal Antibody (HA217014)

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Vista general
Número de catálogoHA217014
Descripción
Anti-Human RCC2 Polyclonal Antibody (HA217014) is a rabbit polyclonal antibody detecting Protein RCC2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RCC2 (Glu89-Arg501).
Objetivo Protein RCC2, Telophase disk protein of 60 kDa, RCC2, RCC1-like protein TD-60, KIAA1470, TD60
Purificación Purified by antigen affinity column.
Número de acceso Q9P258
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Protein RCC2 is a ~56 kDa protein. Multifunctional protein that may affect its functions by regulating the activity of small GTPases, such as RAC1 and RALA. Required for normal progress through the cell cycle, both during interphase and during mitosis. Required for the presence of normal levels of MAD2L1, AURKB and BIRC5 on inner centromeres during mitosis, and for normal attachment of kinetochores to mitotic spindles. Required for normal organization of the microtubule cytoskeleton in interphase cells. Functions as guanine nucleotide exchange factor (GEF) for RALA.

1. Mollinari, C. et al. (2003) Developmental cell 5, 295-307. PMID: 12919680
2. Williamson, RC. et al. (2014) Journal of cell science 127, 4292-307. PMID: 25074804
3. Papini, D. et al. (2015) Nature communications 6, 7678. PMID: 26158537
4. Song, C. et al. (2018) Oncogene 37, 8-17. PMID: 28869598
5. Yenjerla, M. et al. (2013) Cell cycle (Georgetown, Tex.) 12, 837-41. PMID: 23388455
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human RCC2 Polyclonal Antibody

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