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Anti-Human RCOR1 Polyclonal Antibody (HP659014)

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Anti-Human RCOR1 Polyclonal Antibody
Anti-Human RCOR1 Polyclonal Antibody
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Vista general
Número de catálogoHP659014
Descripción
Anti-Human RCOR1 Polyclonal Antibody (HP659014) is a rabbit polyclonal antibody detecting RCOR1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RCOR1 (Asn141-Glu266).
Objetivo RCOR1, REST corepressor 1, RCOR, Protein CoREST, KIAA0071
Purificación Purified by antigen affinity column.
Número de acceso Q9UKL0
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

REST corepressor 1 (RCOR1) is a ~53 kDa protein. Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome.

Nota For research use only.
Imágenes
  • Anti-Human RCOR1 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-RCOR1 polyclonal antibody at 1μg/ml on various samples.
    Lane 1: Molt-4 cell lysate
    Lane 2: HT-29 cell lysate
    Lane 3: Mouse brain lysate
    Lane 4: Mouse testis lysate
    Lane 5: Rat brain lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human RCOR1 Polyclonal Antibody

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