Anti-Human RCOR1 Polyclonal Antibody (HP659014)

Name: Anti-Human RCOR1 Polyclonal Antibody
Brand: abinScience
SKU: HP659014
Price: 96 USD
Availability: InStock

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Обзор

Каталожный номер

HP659014

Описание

Anti-Human RCOR1 Polyclonal Antibody (HP659014) is a rabbit polyclonal antibody detecting RCOR1 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human RCOR1 (Asn141-Glu266).

Цель

RCOR1, REST corepressor 1, RCOR, Protein CoREST, KIAA0071

Очистка

Purified by antigen affinity column.

Номер доступа

Q9UKL0

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

REST corepressor 1 (RCOR1) is a ~53 kDa protein. Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome.

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-RCOR1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Molt-4 cell lysate
Lane 2: HT-29 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Mouse testis lysate
Lane 5: Rat brain lysate

Ссылки

Даташит

Anti-Human RCOR1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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Наборы для анализа

Anti-Human RCOR1 Polyclonal Antibody (HP659014)

Обзор

Изображения

Ссылки

Даташит

SDS