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Anti-Human RGS10 Polyclonal Antibody (HT099014)

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Vista general
Número de catálogoHT099014
Descripción
Anti-Human RGS10 Polyclonal Antibody (HT099014) is a rabbit polyclonal antibody detecting RGS10 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human RGS10 (Ser31-Thr181).
Objetivo Regulator of G-protein signaling 10, RGS10, RGS10
Purificación Purified by antigen affinity column.
Número de acceso O43665
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Regulator of G-protein signaling 10 (RGS10) is a ~21 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein.

1. Tu, Y. et al. (1999) The Journal of biological chemistry 274, 38260-7. PMID: 10608901
2. Burgon, PG. et al. (2001) The Journal of biological chemistry 276, 32828-34. PMID: 11443111
3. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541
4. Hunt, TW. et al. (1996) Nature 383, 175-7. PMID: 8774883
5. Tu, Y. et al. (1997) Science (New York, N.Y.) 278, 1132-5. PMID: 9353196
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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