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| カタログ番号 | HT099014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RGS10 Polyclonal Antibody (HT099014) is a rabbit polyclonal antibody detecting RGS10 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RGS10 (Ser31-Thr181). | ||||||||
| ターゲット | Regulator of G-protein signaling 10, RGS10, RGS10 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43665 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Regulator of G-protein signaling 10 (RGS10) is a ~21 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein. 1. Tu, Y. et al. (1999) The Journal of biological chemistry 274, 38260-7. PMID: 10608901 2. Burgon, PG. et al. (2001) The Journal of biological chemistry 276, 32828-34. PMID: 11443111 3. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541 4. Hunt, TW. et al. (1996) Nature 383, 175-7. PMID: 8774883 5. Tu, Y. et al. (1997) Science (New York, N.Y.) 278, 1132-5. PMID: 9353196 | ||||||||
| 注意事項 | For research use only. |
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