

| Каталожный номер | HT099014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human RGS10 Polyclonal Antibody (HT099014) is a rabbit polyclonal antibody detecting RGS10 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RGS10 (Ser31-Thr181). | ||||||||
| Цель | Regulator of G-protein signaling 10, RGS10, RGS10 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O43665 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||||||
| Информация об использовании продукта |
| ||||||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Regulator of G-protein signaling 10 (RGS10) is a ~21 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein. 1. Tu, Y. et al. (1999) The Journal of biological chemistry 274, 38260-7. PMID: 10608901 2. Burgon, PG. et al. (2001) The Journal of biological chemistry 276, 32828-34. PMID: 11443111 3. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541 4. Hunt, TW. et al. (1996) Nature 383, 175-7. PMID: 8774883 5. Tu, Y. et al. (1997) Science (New York, N.Y.) 278, 1132-5. PMID: 9353196 | ||||||||
| Примечание | For research use only. |
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский