

| Número de catálogo | HP563014 | ||||||||
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| Descripción |
Anti-Human RGS17 Polyclonal Antibody (HP563014) is a rabbit polyclonal antibody detecting RGS17 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human RGS17 (Thr74-Ser210). | ||||||||
| Objetivo | RGS17, Regulator of G-protein signaling 17, RGSZ2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9UGC6 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Regulator of G-protein signaling 17 (RGS17) is a ~24 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins. 1. Mao, H. et al. (2004) The Journal of biological chemistry 279, 26314-22. PMID: 15096504 | ||||||||
| Nota | For research use only. |
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