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Anti-Human RGS2 Polyclonal Antibody (HW831014)

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Aperçu
Numéro de catalogueHW831014
Description
Anti-Human RGS2 Polyclonal Antibody (HW831014) is a rabbit polyclonal antibody detecting RGS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human RGS2 (Ser73-Lys201).
Cible G0S8, Regulator of G-protein signaling 2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, RGS2
Purification Purified by antigen affinity column.
Numéro d'accès P41220
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Regulator of G-protein signaling 2 (RGS2) is a ~24 kDa protein. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle.

1. Cunningham, ML. et al. (2001) The Journal of biological chemistry 276, 5438-44. PMID: 11063746
2. Kimple, AJ. et al. (2009) The Journal of biological chemistry 284, 19402-11. PMID: 19478087
3. Phan, HTN. et al. (2017) Molecular pharmacology 92, 451-458. PMID: 28784619
4. Nguyen, CH. et al. (2009) The Journal of cell biology 186, 755-65. PMID: 19736320
Note For research use only.
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Reférences
Fiche technique
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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