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| カタログ番号 | HW831014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RGS2 Polyclonal Antibody (HW831014) is a rabbit polyclonal antibody detecting RGS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RGS2 (Ser73-Lys201). | ||||||||
| ターゲット | G0S8, Regulator of G-protein signaling 2, Cell growth-inhibiting gene 31 protein, G0/G1 switch regulatory protein 8, RGS2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P41220 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Regulator of G-protein signaling 2 (RGS2) is a ~24 kDa protein. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. It is involved in the negative regulation of the angiotensin-activated signaling pathway. Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle. 1. Cunningham, ML. et al. (2001) The Journal of biological chemistry 276, 5438-44. PMID: 11063746 2. Kimple, AJ. et al. (2009) The Journal of biological chemistry 284, 19402-11. PMID: 19478087 3. Phan, HTN. et al. (2017) Molecular pharmacology 92, 451-458. PMID: 28784619 4. Nguyen, CH. et al. (2009) The Journal of cell biology 186, 755-65. PMID: 19736320 | ||||||||
| 注意事項 | For research use only. |
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