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| カタログ番号 | HY021013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | Blocking, ELISA, ICC | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | K42-41L | ||||
| ターゲット | Rhodopsin, OPN2, Opsin-2, RHO | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P08100 | ||||
| RRID | Anti-Human RHO/Rhodopsin Antibody (K42-41L) (abinScience Cat# HY021013, RRID:AB_3726901) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Rhodopsin is a ~38 kDa protein. Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of the chromophore 11-cis-retinal to all-trans-retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Sieving, PA. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 880-4. PMID: 7846071 _x005F_x005F_x000D_
_x005F_x005F_x000D_
2. Rao, VR. et al. (1994) Nature 367, 639-42. PMID: 8107847 _x005F_x005F_x000D_
_x005F_x005F_x000D_
3. Noorwez, SM. et al. (2003) The Journal of biological chemistry 278, 14442-14450. PMID: 12566452 _x005F_x005F_x000D_
_x005F_x005F_x000D_
4. Dryja, TP. et al. (1990) The New England journal of medicine 323, 1302-7. PMID: 2215617 _x005F_x005F_x000D_
_x005F_x005F_x000D_
5. Kang, Y. et al. (2015) Nature 523, 561-7. PMID: 26200343 _x005F_x005F_x000D_
_x005F_x005F_x000D_
6. He, Y. et al. (2017) Cell research 27, 728-747. PMID: 28524165 _x005F_x005F_x000D_
_x005F_x005F_x000D_
7. Zhou, XE. et al. (2017) Cell 170, 457-469.e13. PMID: 28753425 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human RHO/Rhodopsin Antibody (K42-41L)
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中国武漢市深敦寺路666号C棟、武漢、430206
