

| Numéro de catalogue | HP993014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RILP Polyclonal Antibody (HP993014) is a rabbit polyclonal antibody detecting RILP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human RILP (Ser21-Gln180). | ||||||||
| Cible | Rab-interacting lysosomal protein, RILP | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q96NA2 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Rab-interacting lysosomal protein (RILP) is a ~44 kDa protein. Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes. 1. Cantalupo, G. et al. (2001) The EMBO journal 20, 683-93. PMID: 11179213 2. Jordens, I. et al. (2001) Current biology : CB 11, 1680-5. PMID: 11696325 3. Harrison, RE. et al. (2003) Molecular and cellular biology 23, 6494-506. PMID: 12944476 4. Wang, T. et al. (2004) Molecular biology of the cell 15, 815-26. PMID: 14668488 5. Starling, GP. et al. (2016) EMBO reports 17, 823-41. PMID: 27113757 | ||||||||
| Note | For research use only. |
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