

| Número de catálogo | HV201014 | ||||||||
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| Descripción |
Anti-Human RIOK1 Polyclonal Antibody (HV201014) is a rabbit polyclonal antibody detecting RIOK1. Suitable for Human.
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human RIOK1 (Thr180-Val479). | ||||||||
| Objetivo | EC:2.7.11.1, EC:3.6.1.-, RIO kinase 1, RIO1, RIOK1, Serine/threonine-protein kinase RIO1 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9BRS2 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Serine/threonine-protein kinase RIO1 (RIOK1) is a ~65 kDa protein. Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. 1. Widmann, B. et al. (2012) Molecular biology of the cell 23, 22-35. PMID: 22072790 2. Guderian, G. et al. (2011) The Journal of biological chemistry 286, 1976-86. PMID: 21081503 | ||||||||
| Nota | For research use only |
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