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| カタログ番号 | HV201014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RIOK1 Polyclonal Antibody (HV201014) is a rabbit polyclonal antibody detecting RIOK1. Suitable for Human.
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RIOK1 (Thr180-Val479). | ||||||||
| ターゲット | EC:2.7.11.1, EC:3.6.1.-, RIO kinase 1, RIO1, RIOK1, Serine/threonine-protein kinase RIO1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9BRS2 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Serine/threonine-protein kinase RIO1 (RIOK1) is a ~65 kDa protein. Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in processing of 18S-E pre-rRNA to the mature 18S rRNA. Required for the recycling of NOB1 and PNO1 from the late 40S precursor. The association with the very late 40S subunit intermediate may involve a translation-like checkpoint point cycle preceeding the binding to the 60S ribosomal subunit. Despite the protein kinase domain is proposed to act predominantly as an ATPase. 1. Widmann, B. et al. (2012) Molecular biology of the cell 23, 22-35. PMID: 22072790 2. Guderian, G. et al. (2011) The Journal of biological chemistry 286, 1976-86. PMID: 21081503 | ||||||||
| 注意事項 | For research use only |
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