

| Número de catálogo | HP593014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human RIOX2 (Ser37-Ser257). | ||||||||
| Objetivo | ROX, MDIG, Nucleolar protein 52, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, Ribosomal oxygenase 2, MINA, Histone lysine demethylase MINA, Ribosomal oxygenase MINA, MYC-induced nuclear antigen, RIOX2, 60S ribosomal protein L27a histidine hydroxylase, Mineral dust-induced gene protein, NO52, MINA53 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q8IUF8 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Ribosomal oxygenase 2 (RIOX2) is a ~52 kDa protein. Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-RIOX2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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