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| カタログ番号 | HP593014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RIOX2 (Ser37-Ser257). | ||||||||
| ターゲット | ROX, MDIG, Nucleolar protein 52, Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, Ribosomal oxygenase 2, MINA, Histone lysine demethylase MINA, Ribosomal oxygenase MINA, MYC-induced nuclear antigen, RIOX2, 60S ribosomal protein L27a histidine hydroxylase, Mineral dust-induced gene protein, NO52, MINA53 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8IUF8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ribosomal oxygenase 2 (RIOX2) is a ~52 kDa protein. Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-RIOX2 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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