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| カタログ番号 | HF712014 | ||||||||
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| 説明 |
Anti-Human RNASEH1 Polyclonal Antibody (HF712014) is a rabbit polyclonal antibody detecting RNASEH1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RNASEH1 (Asp138-Asp286). | ||||||||
| ターゲット | RNase H1, RNASEH1, RNH1, Ribonuclease H type II, Ribonuclease H1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O60930 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ribonuclease H1 (RNASEH1) is a ~32 kDa protein. Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II. 1. Wu, H. et al. (1999) The Journal of biological chemistry 274, 28270-8. PMID: 10497183 2. Skourti-Stathaki, K. et al. (2011) Molecular cell 42, 794-805. PMID: 21700224 | ||||||||
| 注意事項 | For research use only. |
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