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Anti-Human RNF13 Polyclonal Antibody (HT135014)

Anti-Human RNF13 Polyclonal Antibody
Anti-Human RNF13 Polyclonal Antibody
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概要
カタログ番号HT135014
説明
Anti-Human RNF13 Polyclonal Antibody (HT135014) is a rabbit polyclonal antibody detecting RNF13 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human, Mouse, Rat
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human RNF13 (Glu33-Glu175).
ターゲット E3 ubiquitin-protein ligase RNF13, 2.3.2.27, RING finger protein 13, RNF13, RZF
精製 Purified by antigen affinity column.
アクセッション番号 O43567
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

E3 ubiquitin-protein ligase RNF13 is a ~42 kDa protein. E3 ubiquitin-protein ligase that regulates cell proliferation. Involved in apoptosis regulation. Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA. Also involved in protein trafficking and localization.

1. Zhang, Q. et al. (2009) Cell research 19, 348-57. PMID: 18794910
2. Arshad, M. et al. (2013) The Journal of biological chemistry 288, 8726-8736. PMID: 23378536
3. Edvardson, S. et al. (2019) American journal of human genetics 104, 179-185. PMID: 30595371
4. van Dijk, JR. et al. (2014) The Biochemical journal 459, 27-36. PMID: 24387786
注意事項 For research use only.
イメージ
  • Anti-Human RNF13 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-RNF13 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse brain lysate
    Lane 2: Rat brain lysate

参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Working Solution
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