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Anti-Human RNF43 Recombinant Antibody (SAA1758)
Anti-Human RNF43 Recombinant Antibody (SAA1758)
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Спецификация:
  • 20ug
  • 50ug
  • 100ug
  • 1mg
Количество:
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Обзор
Каталожный номерHP618013
Описание
Anti-Human RNF43 Recombinant Antibody (SAA1758) (HP618013) is a mouse monoclonal antibody detecting RNF43 in ELISA, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовHuman
ПримененияELISA, WB
Хозяинский видMouse
КлоональностьMonoclonal
ИзотипIgG2a, kappa
ID клонаSAA1758
Цель E3 ubiquitin-protein ligase RNF43, RING finger protein 43, RING-type E3 ubiquitin transferase RNF43, RNF43
Уровень эндотоксинов Please contact with the lab for this information.
Чистота >95% as determined by SDS-PAGE.
Очистка Protein A/G purified from cell culture supernatant.
Номер доступа Q68DV7
RRID Anti-Human RNF43 Antibody (SAA1758) (abinScience Cat# HP618013, RRID:AB_3727519)
Форма Liquid
Буфер хранения 0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:2000-1:20000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон

E3 ubiquitin-protein ligase RNF43 is a ~85 kDa protein. E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification.

1. Sugiura, T. et al. (2008) Experimental cell research 314, 1519-28. PMID: 18313049
2. Hao, HX. et al. (2012) Nature 485, 195-200. PMID: 22575959
3. Koo, BK. et al. (2012) Nature 488, 665-9. PMID: 22895187
Примечание For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Изображения
  • Anti-Human RNF43 Recombinant Antibody (SAA1758)

    Western blot

    Western blot analysis was performed using anti-mouse RNF43 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: ATG11865 200ng
    Lane 2: negative control

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Working Solution
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