Anti-Human RNH1 Polyclonal Antibody (HY509014)

Name: Anti-Human RNH1 Polyclonal Antibody
Brand: abinScience
SKU: HY509014
Price: 96 USD
Availability: InStock

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20ug
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Número de catálogo

HY509014

Descripción

Anti-Human RNH1 Polyclonal Antibody (HY509014) is a rabbit polyclonal antibody detecting RNH1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human RNH1 (Asp218-Glu444).

Objetivo

Ribonuclease inhibitor, Placental ribonuclease inhibitor, Placental RNase inhibitor, Ribonuclease/angiogenin inhibitor 1, RAI, RNH1, PRI, RNH

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

P13489

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Ribonuclease inhibitor (RNH1) is a ~49 kDa protein. Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus.

1. Teufel, DP. et al. (2003) Biochemistry 42, 1451-9. PMID: 12578357

2. Huang, GH. et al. (2003) Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 35, 960-3. PMID: 14515218

3. Lee, FS. et al. (1988) Biochemistry 27, 8545-53. PMID: 3219362

4. Schneider, R. et al. (1988) The EMBO journal 7, 4151-6. PMID: 3243277

5. Shapiro, R. et al. (1987) Proceedings of the National Academy of Sciences of the United States of America 84, 2238-41. PMID: 3470787

6. Chen, CZ. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 1761-6. PMID: 9050852

7. Monti, DM. et al. (2007) FEBS letters 581, 930-4. PMID: 17292889

8. Pizzo, E. et al. (2013) Journal of cell science 126, 4308-19. PMID: 23843625

9. Bai, R. et al. (2020) The EMBO journal 39, e103325. PMID: 32510170

Nota

For research use only

Imágenes

Western blot

Western blot analysis was performed using anti-RNH1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: LO2 cell lysate
Lane 3: Jurkat cell lysate
Lane 4: U87 cell lysate
Lane 5: Raji cell lysate

Referencias

Datasheet

Anti-Human RNH1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human RNH1 Polyclonal Antibody (HY509014)

Vista general

Imágenes

Referencias

Datasheet

SDS