Anti-Human RNH1 Polyclonal Antibody (HY509014)

Name: Anti-Human RNH1 Polyclonal Antibody
Brand: abinScience
SKU: HY509014
Price: 96 USD
Availability: InStock

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Каталожный номер

HY509014

Описание

Anti-Human RNH1 Polyclonal Antibody (HY509014) is a rabbit polyclonal antibody detecting RNH1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human RNH1 (Asp218-Glu444).

Цель

Ribonuclease inhibitor, Placental ribonuclease inhibitor, Placental RNase inhibitor, Ribonuclease/angiogenin inhibitor 1, RAI, RNH1, PRI, RNH

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P13489

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Ribonuclease inhibitor (RNH1) is a ~49 kDa protein. Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis. Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress. Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus.

1. Teufel, DP. et al. (2003) Biochemistry 42, 1451-9. PMID: 12578357

2. Huang, GH. et al. (2003) Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 35, 960-3. PMID: 14515218

3. Lee, FS. et al. (1988) Biochemistry 27, 8545-53. PMID: 3219362

4. Schneider, R. et al. (1988) The EMBO journal 7, 4151-6. PMID: 3243277

5. Shapiro, R. et al. (1987) Proceedings of the National Academy of Sciences of the United States of America 84, 2238-41. PMID: 3470787

6. Chen, CZ. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 1761-6. PMID: 9050852

7. Monti, DM. et al. (2007) FEBS letters 581, 930-4. PMID: 17292889

8. Pizzo, E. et al. (2013) Journal of cell science 126, 4308-19. PMID: 23843625

9. Bai, R. et al. (2020) The EMBO journal 39, e103325. PMID: 32510170

Примечание

For research use only

Изображения

Western blot

Western blot analysis was performed using anti-RNH1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: LO2 cell lysate
Lane 3: Jurkat cell lysate
Lane 4: U87 cell lysate
Lane 5: Raji cell lysate

Ссылки

Даташит

Anti-Human RNH1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human RNH1 Polyclonal Antibody (HY509014)

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Изображения

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