

| Numéro de catalogue | HP898014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human RPGRIP1L Polyclonal Antibody (HP898014) is a rabbit polyclonal antibody detecting RPGRIP1L in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human RPGRIP1L (Glu202-Gln450). | ||||||||
| Cible | NPHP8, RPGR-interacting protein 1-like protein, FTM, KIAA1005, Protein fantom, Nephrocystin-8, RPGRIP1L, RPGRIP1-like protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q68CZ1 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Protein fantom (RPGRIP1L) is a ~151 kDa protein. Negatively regulates signaling through the G-protein coupled thromboxane A2 receptor (TBXA2R). May be involved in mechanisms like programmed cell death, craniofacial development, patterning of the limbs, and formation of the left-right axis. Involved in the organization of apical junctions; the function is proposed to implicate a NPHP1-4-8 module. Does not seem to be strictly required for ciliogenesis. Involved in establishment of planar cell polarity such as in cochlear sensory epithelium and is proposed to implicate stabilization of disheveled proteins. 1. Tokue, S. et al. (2009) Prostaglandins & other lipid mediators 89, 8-15. PMID: 19464661 | ||||||||
| Note | For research use only. |
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