

| Каталожный номер | HW786014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human RPL5 Polyclonal Antibody (HW786014) is a rabbit polyclonal antibody detecting RPL5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RPL5 (Arg50-Asn250). | ||||||||
| Цель | RPL5, 60S ribosomal protein L5, Large ribosomal subunit protein uL18 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P46777 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Large ribosomal subunit protein uL18 (RPL5) is a ~34 kDa protein. Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs. 1. Odintsova, TI. et al. (2003) Journal of protein chemistry 22, 249-58. PMID: 12962325 2. Gazda, HT. et al. (2008) American journal of human genetics 83, 769-80. PMID: 19061985 3. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 4. Sloan, KE. et al. (2013) Cell reports 5, 237-47. PMID: 24120868 | ||||||||
| Примечание | For research use only. |
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