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| カタログ番号 | HB915014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human RPS3 Polyclonal Antibody (HB915014) is a rabbit polyclonal antibody detecting RPS3 in ELISA, IHC, WB. Suitable for Ambystoma mexicanum, Bovine, Dog, Human, and Ictalurus punctatus.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human RPS3 (Met1-Lys187). | ||||||||
| ターゲット | Small ribosomal subunit protein uS3, RPS3, 40S ribosomal protein S3 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P23396 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Small ribosomal subunit protein uS3 (RPS3) is a ~26 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Vladimirov, SN. et al. (1996) European journal of biochemistry 239, 144-9. PMID: 8706699 3. Kim, J. et al. (1995) The Journal of biological chemistry 270, 13620-9. PMID: 7775413 4. Kim, SH. et al. (2005) Biochemical and biophysical research communications 328, 962-7. PMID: 15707971 5. Hegde, V. et al. (2004) DNA repair 3, 121-6. PMID: 14706345 6. Balyeva, KE. et al. (2008) Molekuliarnaia biologiia 42, 314-22. PMID: 18610840 7. Hegde, V. et al. (2004) Biochemistry 43, 14211-7. PMID: 15518571 8. Ko, SI. et al. (2008) Mutation research 648, 54-64. PMID: 18973764 | ||||||||
| 注意事項 | For research use only. |
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