

| Каталожный номер | HB915014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human RPS3 Polyclonal Antibody (HB915014) is a rabbit polyclonal antibody detecting RPS3 in ELISA, IHC, WB. Suitable for Ambystoma mexicanum, Bovine, Dog, Human, and Ictalurus punctatus.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RPS3 (Met1-Lys187). | ||||||||
| Цель | Small ribosomal subunit protein uS3, RPS3, 40S ribosomal protein S3 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P23396 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Small ribosomal subunit protein uS3 (RPS3) is a ~26 kDa protein. Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). 1. Anger, AM. et al. (2013) Nature 497, 80-5. PMID: 23636399 2. Vladimirov, SN. et al. (1996) European journal of biochemistry 239, 144-9. PMID: 8706699 3. Kim, J. et al. (1995) The Journal of biological chemistry 270, 13620-9. PMID: 7775413 4. Kim, SH. et al. (2005) Biochemical and biophysical research communications 328, 962-7. PMID: 15707971 5. Hegde, V. et al. (2004) DNA repair 3, 121-6. PMID: 14706345 6. Balyeva, KE. et al. (2008) Molekuliarnaia biologiia 42, 314-22. PMID: 18610840 7. Hegde, V. et al. (2004) Biochemistry 43, 14211-7. PMID: 15518571 8. Ko, SI. et al. (2008) Mutation research 648, 54-64. PMID: 18973764 | ||||||||
| Примечание | For research use only. |
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