Anti-Human S100A4 Recombinant Antibody (5C3) (HB727013)

Name: Anti-Human S100A4 Recombinant Antibody (5C3)
Brand: abinScience
SKU: HB727013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Каталожный номер	HB727013
Бренд	abinScience
Реактивность видов	Monkey, Macaca mulatta (Rhesus macaque)
Применения	FuncS, IHC, Neut, Inhib
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	5C3
Цель	Protein S100-A4, Calvasculin, Metastasin, Placental calcium-binding protein, Protein Mts1, S100 calcium-binding protein A4, S100A4, CAPL, MTS1
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P26447, P07091
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Protein S100-A4 (S100A4) is a ~11 kDa protein. Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy. Increases cell motility and invasiveness by interacting with non-muscle myosin heavy chain (NMMHC) IIA/MYH9. Mechanistically, promotes filament depolymerization and increases the amount of soluble myosin-IIA, resulting in the formation of stable protrusions facilitating chemotaxis. Also modulates the pro-apoptotic function of TP53 by binding to its C-terminal transactivation domain within the nucleus and reducing its protein levels. Within the extracellular space, stimulates cytokine production including granulocyte colony-stimulating factor and CCL24 from T-lymphocytes. 1. Li, ZH. et al. (2006) Cancer research 66, 5173-80. PMID: 16707441 2. Orre, LM. et al. (2013) Oncogene 32, 5531-40. PMID: 23752197 3. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770 4. Dukhanina, EA. et al. (2015) Cell cycle (Georgetown, Tex.) 14, 3635-43. PMID: 26654597
Примечание	For research use only

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human S100A4 Antibody (5C3)

Ссылки

Даташит

Anti-Human S100A4 Recombinant Antibody (5C3).pdf

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