Anti-Human S1PR4 Recombinant Antibody (SAA1540) (HF811013)

Name: Anti-Human S1PR4 Recombinant Antibody (SAA1540)
Brand: abinScience
SKU: HF811013
Price: 196 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HF811013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1540

Цель

S1P receptor 4, S1P receptor Edg-6, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor 4, EDG6, Sphingosine 1-phosphate receptor Edg-6, S1P4, S1PR4

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

O95977

RRID

Anti-Human S1PR4 Antibody (SAA1540) (abinScience Cat# HF811013, RRID:AB_3727301)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Sphingosine 1-phosphate receptor 4 (S1PR4) is a ~41 kDa protein. G protein-coupled receptor highly expressed in immune cells, where it regulates immune response and cytokine production. Functions as a receptor for the lysosphingolipid sphingosine-1-phosphate (S1P). Upon S1P binding, promotes regulatory T-cell differentiation and enhances fatty acid oxidation, through activation of the NRF2/PPARA signaling pathway. Modulates also M1 macrophage activation through interaction with FPR2 and the JNK signaling, contributing to the inflammatory response. In addition, facilitates early neutrophil mobilization and vascular activation during inflammation, promoting lymphocyte recruitment to draining lymph nodes and supporting the development of germinal centers for an effective adaptive immune response.

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human S1PR4 Antibody (SAA1540)

Ссылки

Даташит

Anti-Human S1PR4 Recombinant Antibody (SAA1540).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа