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Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014)

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Aperçu
Numéro de catalogueHP511014
Description
Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014) is a rabbit polyclonal antibody detecting SR-BI in ELISA, IHC, WB. Suitable for Human, Pig, Dog, and Cat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human SCARB1/SR-BI/CLA-1/SRB1 (Ile61-Gly424).
Cible Scavenger receptor class B member 1, SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36, SCARB1, CD36L1, CLA1
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q8WTV0, Q8SQC1
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Scavenger receptor class B member 1 (SCARB1/SR-BI) is a ~60 kDa protein. Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity.

1. Kawasaki, Y. et al. (2002) The Journal of biological chemistry 277, 27559-66. PMID: 12016218
2. Tai, ES. et al. (2003) Clinical genetics 63, 53-8. PMID: 12519372
3. Vergeer, M. et al. (2011) The New England journal of medicine 364, 136-45. PMID: 21226579
4. Zanoni, P. et al. (2016) Science (New York, N.Y.) 351, 1166-71. PMID: 26965621
Note For research use only.
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Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody

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