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| カタログ番号 | HP511014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SCARB1/SR-BI/CLA-1/SRB1 Polyclonal Antibody (HP511014) is a rabbit polyclonal antibody detecting SR-BI in ELISA, IHC, WB. Suitable for Human, Pig, Dog, and Cat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SCARB1/SR-BI/CLA-1/SRB1 (Ile61-Gly424). | ||||||||
| ターゲット | Scavenger receptor class B member 1, SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36, SCARB1, CD36L1, CLA1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8WTV0, Q8SQC1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Scavenger receptor class B member 1 (SCARB1/SR-BI) is a ~60 kDa protein. Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. 1. Kawasaki, Y. et al. (2002) The Journal of biological chemistry 277, 27559-66. PMID: 12016218 2. Tai, ES. et al. (2003) Clinical genetics 63, 53-8. PMID: 12519372 3. Vergeer, M. et al. (2011) The New England journal of medicine 364, 136-45. PMID: 21226579 4. Zanoni, P. et al. (2016) Science (New York, N.Y.) 351, 1166-71. PMID: 26965621 | ||||||||
| 注意事項 | For research use only. |
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