Anti-Human SCN11A Recombinant Antibody (SAA1857) (HA935013)

Name: Anti-Human SCN11A Recombinant Antibody (SAA1857)
Brand: abinScience
SKU: HA935013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HA935013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1857

Objetivo

SCN11A, hNaN, SNS2, PN5, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, SCN12A, Sodium channel protein type 11 subunit alpha, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9UI33

RRID

Anti-Human SCN11A Antibody (SAA1857) (abinScience Cat# HA935013, RRID:AB_3727620)
_x005F_x005F_x000D_

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Sodium channel protein type 11 subunit alpha (SCN11A) is a ~204 kDa protein. Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization.

1. Dib-Hajj, SD. et al. (1999) FEBS letters 462, 117-20. PMID: 10580103

2. Blum, R. et al. (2002) Nature 419, 687-93. PMID: 12384689

3. Leipold, E. et al. (2013) Nature genetics 45, 1399-404. PMID: 24036948

4. Huang, J. et al. (2014) Brain : a journal of neurology 137, 1627-42. PMID: 24776970

5. Han, C. et al. (2015) Neuromolecular medicine 17, 158-69. PMID: 25791876

6. Leipold, E. et al. (2015) Nature communications 6, 10049. PMID: 26645915

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human SCN11A Antibody (SAA1857)

Referencias

Datasheet

Anti-Human SCN11A Recombinant Antibody (SAA1857).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo