Anti-Human SCN11A Recombinant Antibody (SAA1857) (HA935013)

Name: Anti-Human SCN11A Recombinant Antibody (SAA1857)
Brand: abinScience
SKU: HA935013
Price: 196 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HA935013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1857

Cible

SCN11A, hNaN, SNS2, PN5, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, SCN12A, Sodium channel protein type 11 subunit alpha, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9UI33

RRID

Anti-Human SCN11A Antibody (SAA1857) (abinScience Cat# HA935013, RRID:AB_3727620)
_x005F_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Sodium channel protein type 11 subunit alpha (SCN11A) is a ~204 kDa protein. Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization.

1. Dib-Hajj, SD. et al. (1999) FEBS letters 462, 117-20. PMID: 10580103

2. Blum, R. et al. (2002) Nature 419, 687-93. PMID: 12384689

3. Leipold, E. et al. (2013) Nature genetics 45, 1399-404. PMID: 24036948

4. Huang, J. et al. (2014) Brain : a journal of neurology 137, 1627-42. PMID: 24776970

5. Han, C. et al. (2015) Neuromolecular medicine 17, 158-69. PMID: 25791876

6. Leipold, E. et al. (2015) Nature communications 6, 10049. PMID: 26645915

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human SCN11A Antibody (SAA1857)

Reférences

Fiche technique

Anti-Human SCN11A Recombinant Antibody (SAA1857).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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