中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HA935013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1857 | ||||
| ターゲット | SCN11A, hNaN, SNS2, PN5, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, SCN12A, Sodium channel protein type 11 subunit alpha, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9UI33 | ||||
| RRID | Anti-Human SCN11A Antibody (SAA1857) (abinScience Cat# HA935013, RRID:AB_3727620) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Sodium channel protein type 11 subunit alpha (SCN11A) is a ~204 kDa protein. Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization. 1. Dib-Hajj, SD. et al. (1999) FEBS letters 462, 117-20. PMID: 10580103 2. Blum, R. et al. (2002) Nature 419, 687-93. PMID: 12384689 3. Leipold, E. et al. (2013) Nature genetics 45, 1399-404. PMID: 24036948 4. Huang, J. et al. (2014) Brain : a journal of neurology 137, 1627-42. PMID: 24776970 5. Han, C. et al. (2015) Neuromolecular medicine 17, 158-69. PMID: 25791876 6. Leipold, E. et al. (2015) Nature communications 6, 10049. PMID: 26645915 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human SCN11A Antibody (SAA1857)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
