Anti-Human SCN11A Recombinant Antibody (SAA1857) (HA935013)

Name: Anti-Human SCN11A Recombinant Antibody (SAA1857)
Brand: abinScience
SKU: HA935013
Price: 196 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HA935013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1857

Цель

SCN11A, hNaN, SNS2, PN5, Sodium channel protein type XI subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.9, SCN12A, Sodium channel protein type 11 subunit alpha, Sensory neuron sodium channel 2, Peripheral nerve sodium channel 5

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q9UI33

RRID

Anti-Human SCN11A Antibody (SAA1857) (abinScience Cat# HA935013, RRID:AB_3727620)
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Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Sodium channel protein type 11 subunit alpha (SCN11A) is a ~204 kDa protein. Sodium channel mediating the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Involved in membrane depolarization during action potential in nociceptors which function as key relay stations for the electrical transmission of pain signals from the periphery to the central nervous system. Also involved in rapid BDNF-evoked neuronal depolarization.

1. Dib-Hajj, SD. et al. (1999) FEBS letters 462, 117-20. PMID: 10580103

2. Blum, R. et al. (2002) Nature 419, 687-93. PMID: 12384689

3. Leipold, E. et al. (2013) Nature genetics 45, 1399-404. PMID: 24036948

4. Huang, J. et al. (2014) Brain : a journal of neurology 137, 1627-42. PMID: 24776970

5. Han, C. et al. (2015) Neuromolecular medicine 17, 158-69. PMID: 25791876

6. Leipold, E. et al. (2015) Nature communications 6, 10049. PMID: 26645915

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human SCN11A Antibody (SAA1857)

Ссылки

Даташит

Anti-Human SCN11A Recombinant Antibody (SAA1857).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа