

| Numéro de catalogue | HD658014 | ||||||||
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| Description |
Anti-Human SCNN1D Polyclonal Antibody (HD658014) is a rabbit polyclonal antibody detecting SCNN1D. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SCNN1D (Arg277-Tyr683). | ||||||||
| Cible | Amiloride-sensitive sodium channel subunit delta, DNACH, Delta-ENaC, Delta-NaCH, ENaCD, Epithelial Na(+) channel subunit delta, Epithelial sodium channel subunit delta, Nonvoltage-gated sodium channel 1 subunit delta, SCNED, SCNN1D | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P51172 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Epithelial sodium channel subunit delta (SCNN1D) is a ~87 kDa protein. Potential alternative pore-forming subunit of the epithelial sodium channel (ENaC), capable of replacing the alpha/SCNN1A subunit, creating a more active channel with distinct properties. ENaC functions in epithelial tissues, where it facilitates the electrodiffusion of sodium ions from the extracellular fluid through the apical membrane of cells, with water following osmotically, regulating sodium balance and fluid homeostasis. This subunit could also function independently as a sodium channel or assemble into other tissue-specific heterotrimeric sodium channels. 1. Ji, HL. et al. (2006) The Journal of biological chemistry 281, 8233-41. PMID: 16423824 2. Bangel-Ruland, N. et al. (2010) American journal of respiratory cell and molecular biology 42, 498-505. PMID: 19520916 3. Zhao, RZ. et al. (2012) American journal of physiology. Lung cellular and molecular physiology 302, L1262-72. PMID: 22505667 4. Waldmann, R. et al. (1995) The Journal of biological chemistry 270, 27411-4. PMID: 7499195 | ||||||||
| Note | For research use only |
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